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While the leading causes of calf illness and death within the first few days after delivery are non-infectious physiological disturbances, after that time, the majority of illness and death losses are attributable to infectious conditions.

Dairy production systems in the US have changed considerably over the last several decades due to forces that promote economic efficiency of production and to scientific and technological advances that afford opportunities for change.

Esophageal diseases cause disturbance of food flow through the esophagus due to obstructions from foreign bodies and tumors, inflammation, decreased motility, and compression of the esophagus from intramural or extra-luminal masses.