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Oncology

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Canine proliferative histiocytic disorders (PHD) include nonneoplastic or nonmalignant conditions such as the benign cutaneous histiocytoma of young dogs or the cutaneous and systemic histiocytoses (reactive histiocytic diseases), and malignant proliferations including malignant fibrous histiocytoma, splenic fibrohistiocytic nodules, and histiocytic sarcoma (localized, disseminated, hemophagocytic).

The recognition of the development of potentially malignant tumors arising from injection sites became one of the most significant events in veterinary medicine in the 1980's and beyond. So significant, in fact, that it caused an entire profession to re-evaluate the way preventative medicine should be considered from a medical and an economic perspective.