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Oncology

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Columbia, Mo. -- Researchers at the University of Missouri (MU) College of Veterinary Medicine have started a clinical trial on a human oncology drug which may prove useful in the battle against canine cancer. The drug Attaxol?, which is made by CritiTech in Lawrence, Kan., could be ideal for use in dogs with naturally occurring cancer, says Dr. Kim Seltin, assistant professor of oncology at the MU College of Veterinary Medicine.

Mast cell tumors are the most commonly encountered malignant skin tumor in the dog. They account for 16-21% of all cutaneous tumors and boxers, Boston terriers, Labrador retrievers, beagles and schnauzers are documented to be at increased risk. Alterations in the c-kit receptor (receptor for growth factor SCF) are noted in many high grade tumors. Histologic grade is highly predictive of behavior.

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Head and neck tumors are relatively common in aging cats. Understanding the differential diagnoses in this anatomic area is crucial as the diagnostic and therapeutic approaches may vary. This lecture will discuss feline oral tumors, sinonasal tumors, iris melanoma, Hodgkin's-like lymphoma, salivary gland tumors, tumors of the ear canal, and skin tumors.