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Bone Anchor Pack

Securos introduces their Bone Anchor Pack that keeps the essential items required for a bone anchor (tissue anchor) repair all in one place. T

Medical Task Light

Derungs Medical Lighting introduces a medical task light that offers the maximum light output and natural "daylight" illumination by using a 36-watt, 5400K compact fluorescent lamp.

Osteoarthritis, or degenerative joint disease, is the most prevalent joint disorder in dogs. Mild osteoarthritis may cause subtle gait changes or intermittent lameness. As osteoarthritis severity progresses, the dog may become less active, show visible lameness, experience difficulty rising or lying down, express pain, or experience difficulty posturing to urinate or defecate.

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While osteoarthritis is perceived as a structural disease, the underlying pathology and chronic changes occur at a cellular and molecular level. In this article, we will discuss recent research involving the molecular mechanisms involved in osteoarthritis and newer opportunities for treatment. Key to this knowledge are research tools emerging from the scientific disciplines of functional genomics and molecular biology.

Osteoarthritis is the most common rheumatic disease encountered in small animal practice. No longer is osteoarthritis regarded as a simple consequence of aging and cartilage degeneration, but rather, the pathologic changes of osteoarthritis may result from active biochemical and biomechanical processes partly due to disturbances of the homeostatic mechanisms of anabolic and catabolic pathways. As to the cause of osteoarthritis, there is no one etiology and its cause may be multifactorial. While there are many initiating causes, osteoarthritis is an irreversible process that often results in an end-stage clinical syndrome of the joint.

Osteoarthritis is a common, often-debilitating disease of both animals and humans. It may involve any joint, but the joints most clinically affected are the hip, elbow, shoulder, knee, and spine. It is estimated that one in five dogs will show obvious signs of pain from osteoarthritis; in many more dogs, however, the signs will be subtle or subclinical. In dogs, the most common form of osteoarthritis is canine hip dysplasia. The radiographic prevalence of canine hip dysplasia is as high as 75% in some breeds and the disease can cause pain and dysfunction in affected animals.

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Osteoarthritis is a chronic and potentially debilitating disease involving the disruption of metabolic homeostasis within the articular chondrocyte. Specifically, osteoarthritis involves an increased ratio of cartilage-degrading enzymes (matrix metalloproteinases, or MMPs) to their normal inhibitors, tissue inhibitors of metalloproteinases (TIMPs). It is the imbalance of TIMPs and MMPs that contributes to the pathologic breakdown of cartilage. Dietary fatty acids can help to correct this imbalance by modulating the production of inflammatory mediators.

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A comprehensive weight-loss program that returns overweight dogs to optimal body weight and body condition can improve osteoarthritic dogs' ability to move more normally. In a study conducted at Texas A&M University, moderately overweight to obese dogs lost weight through a combination of a weight-management diet and increased exercise. Based on force-plate gait analysis, the dogs exerted significantly more force on each limb and moved more quickly. The abstract below, published in the proceedings of the 2000 Purina Nutrition Forum, provides additional details.

Osteoarthritis, also called degenerative joint disease, is the most prevalent joint disorder in dogs, affecting as many as 20% of adult dogs. Osteoarthritis is associated with inflammation and increased degradation or loss of proteoglycans from the extracellular matrix, resulting in a morphologic breakdown in articular cartilage.

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Safe Pool Exit

Skamper-Ramp? provides animals with a way out of their water entrapment. The product is easy to assemble and install the company says.

Performance Program

Osborne Industries Inc. and Swine Management Services LLC (SMS) jointly announce a new cooperative agreement between the two companies to provide an offer to users of Porcode? and TEAM? electronic sow feeding and electronic estrous detection system.

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Witness FeLV

Synbiotics announces the USDA approval of their Witness FeLV antigen test kit.

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FORT COLLINS, COLO.-Heska introduces the FVRCP vaccine providing protection against the most prevalent causes of feline upper respiratory disease and feline panleukopenia without needles.

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IV Catheter

Jorgensen Laboratories Inc. introduces the AdvanTive IV catheter.

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Surgical Staplers

Kendall's auto-suture stapling device helps veterinarians perform surgeries with more speed and precision, the company says.

New Vaccines

Solid Tech received licenses to produce and sell three cattle vaccine products.

New Web Site

Abbott Animal Health, a division of Abbott Laboratories, launched a new Web site to communicate its vision and educating the veterinary community on its products and services, according to the company.

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To convince skeptical clients that their pets can eat and drink with an Elizabethan collar on, we took a picture of a patient doing just that and posted the picture by the checkout desk.

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Parasite Dust

Buck Mountain Botanicals offers a parasite dust that is non-mutagenic and non-toxic to warm blooded animals, fish and birds.

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Joint Care

Vitality Systems' Chondro-Flex? Stage 1 for puppies and dogs is available exclusively through veterinarians.

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IV Flush Syringes

Monoject prefilled syringes are heparinized and ready-to-use, saving time and eliminating cross contamination.