Medical

Aspirin (acetylsalicylic acid, ASA) is the salicylate ester of acetic acid and is a weak acid derived from phenol. Aspirin reduces pain and inflammation by reducing prostaglandin and thromboxane synthesis through inhibition of cyclooxygenase. At very high doses, aspirin and other salicylates uncouple oxidative phosphorylation leading to decreased ATP production. Salicylates also affect platelet aggregation.

Congenital portosystemic shunts (PSS) are much more common and certainly much more confusing than we ever imagined. At Texas A&M, we infrequently see the "classic" congenital PSS with the relatively straight forward presentation (i.e., young Yorkie with post prandial hepatic encephalopathy), probably because those cases are efficiently filtered out and never referred to us.

The ASV standards were written to help shelters assess their facilities and strive to make positive changes to better the lives of those animals in their care. Many shelters already meet the requirements, but there may be challenges faced with maintaining some of these standards.

An animal's life can be divided into four stages; pediatric, adult, senior (middle age), and geriatric (senior / super senior). The senior / middle age years represents the transition period between the usually uneventful "healthy" adult years and the traditional "geriatric" age period where serious age related diseases are much more prevalent.

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The goal of orphan puppy and kitten care is to maximize their health, well being, and socialization until they can be placed on a foster mother or adopted. The needs of the healthy young are very simple, water, nutrition and the proper environment. Obviously these husbandry issues are more critical in the newborn and the sick than the healthy 8 week old.

Regurgitation occurs when there is either an anatomic obstruction or a physiologic weakness in the esophagus. In either case, food is retained in the esophagus and, if it passively migrates back into the oropharynx, can be regurgitated. The problem should be diagnosed quickly in an attempt to solve it before the esophagus becomes irreversibly-dilated or the patient experiences an aspiration pneumonia.

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The liver has more biochemical functions than any other organ of the body. It functions in hundreds of diverse metabolic activities including synthesis of plasma proteins; catabolism and storage of carbohydrates; synthesis, degradation, and storage of lipids; detoxification and excretion of many toxic agents; and the formation and elimination of bile.

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Methylxanthines are alkaloids that occur naturally in plants and are found in tea, coffee beans, cola beans, and cocoa beans. The methylxanthines in chocolate include caffeine and theobromine. Some methylxanthines are used therapeutically as bronchodilators including theophylline and aminophylline.

Citalopram is a Selective Serotonin Reuptake Inhibitor (SSRI). The therapeutic dose in dogs is 1 mg/kg PO q 24 h. Per APCC Database: 1 mg/kg depression and 29 mg/kg tremors, seizures. Citalopram overdose results in serotonin syndrome. Serotonin syndrome is a complex group of clinical signs resulting from the over stimulation of serotonin receptors and can include the following:

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Blood component transfusion is generally provided as supportive therapy for correction of one or more hematologic and/or hemostatic deficiencies, until the underlying disease process can be controlled or corrected. Blood component administration and its immediate endpoints often are only one part of a general therapeutic plan.

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Treatment of urinary tract infections offer an example of the hazards and difficulties encountered when initial response is insufficient. Treatment of bacterial UTI offers a good example of how treatment of bacterial infections might be approaches. The goal of drug therapy has been to eliminate bactiuria, but this goal should be modified to include eradication of infection while minimizing the advent of resistance.

Inflammatory lesions may present as visible or palpable lumps, bumps, plaques, ulcers, accumulations of excessive fluid, or as abnormalities in organs that are visualized using imaging techniques. Cytologic examination of these types of lesions may be definitively diagnostic in many cases, or contribute to a diagnosis in other cases. When certain types of infectious agents are present, cytologic examination may be particularly rewarding.

Clinically significant drug interactions are rarely reported in veterinary medicine, however the incidence is probably far greater than is reported. With the introduction of more and more veterinary drugs, as well as the use of more human drugs in animals, the incidence is likely to increase in the next few years.