Neurology

The vast majority of seizures are self-limiting events, with eventual spontaneous return to resting or baseline neurologic function. However, during status epilepticus, a variety of changes occur within cells and networks of cells that result in a situation where the seizure activity becomes self-sustaining.

The clinical manifestation of excessive and/or hypersynchronous neuronal discharge within the brain; may be manifested as episodic impairment or loss of consciousness, abnormal motor phenomena, psychic or sensory disturbances, or autonomic signs such as salivation, vomiting, urination or defecation. Synonyms – convulsion, ictus, fit.

The vestibular system is responsible for the maintenance of balance and equilibrium in the body, and is comprised of a number of anatomic structures. The semicircular canals are located within the thick petrous temporal bone of the skull, and are composed of three bony canals containing membranous ectoderm structures (semicircular ducts) filled with fluid (endolymph).

Lameness, difficulty walking, and reluctance or inability to rise are common presentations for patients presented to small animal practitioners. Disorders of the central and peripheral nervous systems, spine, long bones, joints, tendons, or musculature can all result in these potential signs.

Deciding on a treatment plan for an animal with seizures depends on a number of factors, including the suspected etiologic cause of the seizures, the frequency and severity of the observed seizures, and the financial constraints or intentions of the owner.

Veterinary patients can present for a variety of diseases that impact the neurological system. These patients can require anesthesia for stabilization, diagnostic procedures, or surgical correction of these diseases.

Neurological emergencies are common in small animal practice. As with other body systems, infections, neoplasms, trauma, inflammatory processes, congenital and hereditary diseases all affect the central and peripheral nervous systems causing a range of mild to severe conditions.

Tips for treating dogs with bromide.

Follow Pollux's tale, and discover more about disk disease in cats.

Dr. David Bruyette helps sort through the causes in this case.

What does a cranial nerve deficit indicate?

BSE is defined as a slow developing neurodegenerative disease of cattle that begins insidiously with subtle signs progressing to terminal recumbency. This is a cerebral disease thus signs are consistent with abnormal mentation. Slight changes in behavior include increased apprehension and tactile and auditory hyperesthesia.

Traumatic spinal cord injury.

Seizure: Clinical manifestation of abnormal electrical activity in the cerebral cortex

The neurologic exam is the most important diagnostic test in the evaluation of neurologic disease.

The canine patient presented for apparent pain without an obvious cause can be a diagnostic challenge. Thorough examination is an important step in identifying a source of discomfort and determining appropriate diagnostic testing for further evaluation.

Traumatic brain injury.

The vestibular system functions to maintain an animal's balance and orientation with respect to gravity.

Consider pregabalin as an adjunct to phenobarbital or potassium bromide in poorly controlled dogs.

Why you shouldn't be so quick to diagnose cognitive dysfunction.

Raleigh, N.C. -- A gene linked to a fatal neurodegenerative disease in American Staffordshire terriers was identified by veterinary researchers.

The inability of our veterinary patients to speak to us can make determining the presence of pain a challenging process. Vocalization is often a clear sign that an animal is painful. However, even this can be misleading at times, as animals with brain disorders may vocalize without being painful.

Metronidazole toxicity typically occurs with dosages greater than 60 mg/kg/day. Cerebellar Purkinje cell loss and axonal degeneration may occur. Thus, cerebellar and vestibular signs such as ataxia, hypermetria and nystagmus may be seen with toxicity.

Gait evaluation in the pediatric patient can initially be difficult as puppies first learn to walk and the myelination process matures. As development progresses spinal disorders may become more apparent. Numerous congenital abnormalities resulting in spinal malformation exist.

Infectious diseases of the nervous system are relatively uncommon compared to other neurological abnormalities in adult animals. However, infectious diseases should be placed high on the differential diagnosis list in puppies and kittens.

The neurological examination of puppies and kittens can be challenging. Pediatric patients can be uncooperative and their various stages of development lead to different expectations of normalcy compared to adults.

Seizure disorders in young animals pose different considerations as to etiology and therapeutic decisions compared to adult dogs. Congenital, developmental, metabolic, toxic, infectious and inflammatory causes should be considered more likely in younger dogs and puppies. Seizures are the manifestation of abnormal synchronous electrical activity in the brain and are the most common neurological disorder in dogs.

Staphylococcus is a common cause of discospondylitis. Spinal epidural empyema (i.e. abcess) is most often associated with E. Coli, Bacteriodes spp and S. Intermedius.

A closer look at genetics is offering new insight into disease conditions.

Neurons produce their effect by generating and propagating action potentials. In order to do this, they need to have adequate energy supplies (to maintain resting potential and axonal transport) and appropriate concentrations of electrolytes.