Kurt A. Grimm, DVM, MS, PhD, DACVA, DACVCP
An introduction to the principles of clinical blood gas analysis and interpretation--including two case examples.
An 8-year-old 44-lb (20-kg) spayed female Siberian husky is a poorly regulated diabetic presenting for surgical excision of a grade I fibrosarcoma on the right thoracic wall.
A 5-year-old 37.6-lb (17.1-kg) neutered male border collie has a three-day history of vomiting.
Patient stress is probably a contributing factor in some cases of adverse patient outcome. Stress during induction of anesthesia can increase circulating catecholamine concentration predisposing the heart to arrhythmias.
A continuous rate infusion (CRI) is a dosing regimen used to deliver a constant amount of drug per unit time. The most common CRIs are administered intravenously; however, other methods such as transdermal deliver mimic the characteristics of CRIs.
Alpha 2 adrenergic agonists bind to alpha 2 receptors located in the dorsal horn of the spinal cord and brainstem, modulating the release of substance P, calcitonin gene-related peptide and various other neurotransmitters involved in rostral transmission of nociceptive information.