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When PCR testing is helpful-and when it isn't.
“Polymerase chain reaction (PCR) can be the best diagnostic tool to detect a needle in haystack, but if you only have one needle and the haystack is too big, it can be hard to find, which equates to a negative PCR result in an infected patient. Whenever possible, it is best to do both serology and PCR testing.”
-Edward Breitschwerdt, DVM, DACVIM
From Diagnosing infectious disease