• DVM360_Conference_Charlotte,NC_banner
  • ACVCACVC
  • DVM 360
  • Fetch DVM 360Fetch DVM 360
DVM 360
dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care
dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care
By Role
AssociatesOwnersPractice ManagerStudentsTechnicians
Subscriptions
dvm360 Newsletterdvm360 Magazine
News
All News
Association
Breaking News
Conference Coverage
Education
Equine
FDA
Law & Ethics
Market Trends
Medical
Politics
Products
Recalls
Regulatory
Digital Media
dvm360 LIVE!™
Expert Interviews
The Vet Blast Podcast
Medical World News
Pet Connections
The Dilemma Live
Vet Perspectives™
Weekly Newscast
dvm360 Insights™
Publications
All Publications
dvm360
Firstline
Supplements
Top Recommended Veterinary Products
Vetted
Clinical
All Clinical
Anesthesia
Animal Welfare
Behavior
Cardiology
CBD in Pets
Dentistry
Dermatology
Diabetes
Emergency & Critical Care
Endocrinology
Equine Medicine
Exotic Animal Medicine
Feline Medicine
Gastroenterology
Imaging
Infectious Diseases
Integrative Medicine
Nutrition
Oncology
Ophthalmology
Orthopedics
Pain Management
Parasitology
Pharmacy
Surgery
Toxicology
Urology & Nephrology
Virtual Care
Business
All Business
Business & Personal Finance
Hospital Design
Personnel Management
Practice Finances
Practice Operations
Wellbeing & Lifestyle
Continuing Education
Conferences
Conference Listing
Conference Proceedings
Resources
CBD in Pets
CE Requirements by State
Contests
Veterinary Heroes
Partners
Spotlight Series
Team Meeting in a Box
Toolkit
Top Recommended Veterinary Products
Vet to Vet
  • Contact Us
  • Fetch DVM360 Conference
  • Terms and Conditions
  • Privacy
  • Do Not Sell My Information
  • About Us

© 2023 MJH Life Sciences and dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care. All rights reserved.

Advertisement
By Role
  • Associates
  • Owners
  • Practice Manager
  • Students
  • Technicians
Subscriptions
  • dvm360 Newsletter
  • dvm360 Magazine
  • Contact Us
  • Fetch DVM360 Conference
  • Terms and Conditions
  • Privacy
  • Do Not Sell My Information
  • About Us
  • MJHLS Brand Logo

© 2023 MJH Life Sciences™ and dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care. All rights reserved.

Conditional approval expires for canine cancer drug

December 18, 2015

Marketing for the veterinary drug in the United States must stop as testing continues for Kinavet-CA1.

Five-year conditional approval for Kinavet-CA1 (masitinib mesylate) has ended, according to the U.S. Food and Drug Administration (FDA), and that means AB Science SA must cease marketing the drug in the United States. AB Science reports that testing of the drug will continue until full approval is reached.

The drug was given conditional approval to treat non-resectable Grade II or III cutaneous mast cell tumors in dogs that have not previously received radiotherapy and/or chemotherapy except corticosteroids. AB Science says in a release that the company hopes to to complete the application for full approval by 2016.

Currently, AB Science says it is executing a prospective, multicenter, randomized, placebo-controlled phase 3 study to compare efficacy and safety of masitinib to placebo in the treatment of aggressive mast cell tumors in dogs not previously treated by chemotherapy or radiotherapy. An interim analysis based on the data of 74 dogs showed “statistically significant superiority on Time to Progression (Log-rank, p < 0.001).”

Advertisement

Masitinib is an orally administered tyrosine kinase inhibitor that targets mast cells and macrophages.

Kinavet-CA1 is fully approved in Europe by the European Medicine Agency (EMA) under the brand name Masivet.

Related Content:

OncologyMedicalRegulatoryBreaking News
3 categories of inappetence in dogs
3 categories of inappetence in dogs
UC Davis oral surgeons repair kitten’s severe cleft palate
UC Davis oral surgeons repair kitten’s severe cleft palate
Tips and tricks for diagnosing canine osteoarthritis early
Tips and tricks for diagnosing canine osteoarthritis early

Advertisement

Latest News

Morris Animal Foundation appoints new chief program officer

CDC issues warning over cat-transmitted sporotrichosis

An AI solution is speeding up insurance claims processing

3 categories of inappetence in dogs

View More Latest News
Advertisement