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What not to do when a corneal ulcer fails to heal.
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“When seemingly routine corneal ulcers in dogs fail to heal in a normal period (i.e. seven to 10 days), many veterinarians engage in musical chairs treatment, prescribing one topical antibiotic and then another. Unless specific signs of bacterial infection are present (e.g. progressive stromal loss, a leukocytic infiltrate in the stroma, a melting component associated with the ulcer), switching topical antibiotics is a waste of time and money.”
-Steven R. Hollingsworth, DVM, DACVO
From Practical Matters: How to handle nonhealing corneal ulcers in dogs
