• One Health
  • Pain Management
  • Oncology
  • Anesthesia
  • Geriatric & Palliative Medicine
  • Ophthalmology
  • Anatomic Pathology
  • Poultry Medicine
  • Infectious Diseases
  • Dermatology
  • Theriogenology
  • Nutrition
  • Animal Welfare
  • Radiology
  • Internal Medicine
  • Small Ruminant
  • Cardiology
  • Dentistry
  • Feline Medicine
  • Soft Tissue Surgery
  • Urology/Nephrology
  • Avian & Exotic
  • Preventive Medicine
  • Anesthesiology & Pain Management
  • Integrative & Holistic Medicine
  • Food Animals
  • Behavior
  • Zoo Medicine
  • Toxicology
  • Orthopedics
  • Emergency & Critical Care
  • Equine Medicine
  • Pharmacology
  • Pediatrics
  • Respiratory Medicine
  • Shelter Medicine
  • Parasitology
  • Clinical Pathology
  • Virtual Care
  • Rehabilitation
  • Epidemiology
  • Fish Medicine
  • Diabetes
  • Livestock
  • Endocrinology

Are Disease-Resistant Pigs the Future?

Article

Forget designer babies; let's talk about disease-resistant pigs.

Forget designer babies; let’s talk about disease-resistant pigs. Researchers from the University of Missouri recently teamed with British scientists from Genus, an animal genetics firm, to develop pigs that are resistant to Porcine Reproductive and Respiratory Syndrome Virus (PRRSv), a costly and devastating disease. PRRSv causes reproductive impairment and respiratory disease in pigs of any age. The disease was first detected in the United States in 1987 and to date, no vaccine has been effective against it.

According to the study published in Nature Biotechnology, researchers used precise gene editing to breed pigs that do not produce a specific protein (CD163) necessary for PRRSv to spread. When the researchers exposed the genetically altered pigs to PRRSv, they did not contract the virus. As a result, Reuters.com quoted Genus Chief Scientific Officer Jonathan Lightner as saying that gene editing is "a potential game-changer for the pork industry."

In addition, the researchers did not notice any adverse effects or development changes in the pigs as a result of the genetic alteration. Kevin Wells, co-author of the study and assistant professor of animal sciences at Missouri is quoted as stating, “This discovery could save the swine industry hundreds of millions of dollars every year. It also could have an impact on how we address other substantial diseases in other species.” Although further testing is needed, the researchers signed an exclusive global licensing deal for potential future commercialization of virus-resistant pigs with Genus.

Related Videos
Image Credit: © Przemyslaw Iciak - stock.adobe.com
© dvm360
© dvm360
© 2024 MJH Life Sciences

All rights reserved.