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One hospital found this to be the best method of restraint and anesthesia in cats donating blood.
“After evaluating these different techniques, we considered inhalant anesthesia with sevoflurane to be the most reliable method for immobilizing the cats for blood donation. We also found that administering the inhalant anesthetic through a mask did not interfere with blood collection.”
-H.L. Troyer, DVM; William E. Feeman III, DVM; Toni L. Gray, RVT; and C. Guillermo Couto, DVM, DACVIM
From Comparing chemical restraint and anesthetic protocols used for blood donation in cats: One teaching hospital's experience