Medical

The definition of kidney disease includes any structural or functional change of the kidneys. The kidneys are uniquely susceptible to injury due to the large quantity of blood filtered for each cardiac cycle (20-25% of cardiac output), regional differences in blood supply within the kidney, and a high rate of metabolic activity of renal tubular cells.

Hyperadrenocorticism (HAC) is a commonly diagnosed endocrinopathy in dogs which is caused by persistently high cortisol levels in circulation. Diagnosis and treatment may not be straightforward, and successful management depends upon appropriate evaluation of clinical signs, selection and interpretation of diagnostic tests, and administration and monitoring of therapy.

Albumin is the major determinant of oncotic or colloidal osmotic pressure, the force that holds fluids within the vascular compartment. Most of the important osmotically-active particles in the bloodstream (such as sodium, urea and glucose) are relatively small, and pass freely between the vascular and interstitial compartments, the bodys two major extracellular fluid compartments.