• Hero Banner
  • ACVCACVC
  • DVM 360
  • Fetch DVM 360Fetch DVM 360
DVM 360
dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care
dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care
By Role
AssociatesOwnersPractice ManagerStudentsTechnicians
Subscriptions
dvm360 Newsletterdvm360 Magazine
News
All News
Association
Breaking News
Education
Equine
FDA
Law & Ethics
Market Trends
Medical
Products
Recalls
Regulatory
Digital Media
dvm360 LIVE!™
Expert Interviews
The Vet Blast Podcast
Medical World News
Pet Connections
The Dilemma Live
Vet Perspectives™
Weekly Newscast
dvm360 Insights™
Publications
All Publications
dvm360
Firstline
Supplements
Top Recommended Veterinary Products
Vetted
Clinical
All Clinical
Anesthesia
Animal Welfare
Behavior
Cardiology
CBD in Pets
Dentistry
Dermatology
Diabetes
Emergency & Critical Care
Endocrinology
Equine Medicine
Exotic Animal Medicine
Feline Medicine
Gastroenterology
Imaging
Infectious Diseases
Integrative Medicine
Nutrition
Oncology
Ophthalmology
Orthopedics
Pain Management
Parasitology
Pharmacy
Surgery
Toxicology
Urology & Nephrology
Virtual Care
Business
All Business
Business & Personal Finance
Buying or Selling a Practice
Hospital Design
Leadership & Personal Growth
Personnel Management
Practice Finances
Practice Operations
Technology
Wellbeing & Lifestyle
Continuing Education
Conferences
Live Conferences
Conference News
Conference Proceedings
Resources
CBD in Pets
Contests
Veterinary Heroes
Partners
Spotlight Series
Team Meeting in a Box
Toolkit
Top Recommended Veterinary Products
Vet to Vet
  • Contact Us
  • Fetch DVM360 Conference
  • Terms and Conditions
  • Privacy
  • Do Not Sell My Information
  • About Us

© 2023 MJH Life Sciences and dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care. All rights reserved.

Advertisement
By Role
  • Associates
  • Owners
  • Practice Manager
  • Students
  • Technicians
Subscriptions
  • dvm360 Newsletter
  • dvm360 Magazine
  • Contact Us
  • Fetch DVM360 Conference
  • Terms and Conditions
  • Privacy
  • Do Not Sell My Information
  • About Us
  • MJHLS Brand Logo

© 2023 MJH Life Sciences™ and dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care. All rights reserved.

Journal Scan: An alternative insulin for diabetic dogs

August 20, 2012
Avi Blake, DVM

Some diabetic dogs are insufficiently controlled with NPH insulin. Here's a look at a possible alternative.

Some dogs with diabetes mellitus are insufficiently controlled with NPH insulin, leaving practitioners in search of a longer-acting insulin alternative. The search has become even more difficult since a purified pork source lente insulin was removed from the market by the FDA in 2009.

What they did

In a recent study, six newly diagnosed and 11 insulin-treated diabetic dogs were given recombinant human protamine zinc insulin for 60 days. On days 7, 14, 30, and 60, the dogs were evaluated (history, physical examination including body weight, serum fructosamine concentration, and blood glucose concentration) before and at two-hour intervals (up to 10 hours) after insulin administration.

What they found

Advertisement

The dogs demonstrated significant decreases in mean 10-hour serum blood glucose and serum fructosamine concentrations at day 60, and clinical signs including body weight improved. Hypoglycemia was the only adverse event observed.

Take-home message

The study results suggest that the use of this insulin product is effective in diabetic dogs and offers an alternative to patients poorly controlled with other insulin preparations.

Maggiore AD, Nelson RW, Dennis J, et al. Efficacy of protamine zinc recombinant human insulin for controlling hyperglycemia in dogs with diabetes mellitus. J Vet Intern Med 2012;26(1):109-115.

Link to abstract: http://onlinelibrary.wiley.com/doi/10.1111/j.1939-1676.2011.00861.x/abstract

Related Content:

Endocrinology
Using in-clinic cortisol testing to detect endocrine diseases in dogs
Using in-clinic cortisol testing to detect endocrine diseases in dogs
The American Animal Hospital Association shares new endocrine guidelines
The American Animal Hospital Association shares new endocrine guidelines
Spectrum of care for diabetic patients
Spectrum of care for diabetic patients

Advertisement

Latest News

News wrap-up: This week’s headlines, plus Kansas State University College of Veterinary Medicine presents Temple Grandin, PhD, MS, with an honorary degree

Can our Pride panel answer these LGBTQ+ trivia questions?

Creating inclusive spaces for the LGBTQ+ community in vet med

Happy Pride Month, Hill's launches Prescription Diet ONC Care, and more

View More Latest News
Advertisement