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Try again. While measuring endogenous ACTH can be used as a differentiating test for patients with hyperadrenocorticism of unknown type, it would not likely add new information at this point. The endogenous ACTH concentration is expected to be low in patients with adrenal-dependent disease, but about 20% of dogs that have pituitary-dependent hyperadrenocorticism have variable ACTH concentrations that drop into the low normal or below normal reference range and make differentiation difficult.
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