Higher-concentration cefovecin approved by FDA for certain skin infections in dogs

The FDA has approved Convenia RTU for Dogs (cefovecin injectable suspension), a ready-to-use (RTU) treatment for canine skin infections caused by susceptible strains of Staphylococcus pseudintermedius and Streptococcus canis (group G).¹

According to the FDA, both bacterial species can typically live on a healthy dog's skin without causing harm. However, both are opportunistic pathogens. If scratching, allergies, or injury compromises the skin's protective barrier, the bacteria can multiply rapidly and cause severe infections.¹

Cefovecin sodium, the active ingredient in Convenia RTU for Dogs, is a third-generation cephalosporin and β-lactam antimicrobial that can be used to kill the bacteria if a dog develops an infection.¹ The FDA approved the original Convenia formulation in 2008 to treat skin infections in both dogs and cats.¹

How the new formulation differs

The RTU product contains the same active ingredient as the original product. The FDA announcement highlights 2 differences between the products:

• The RTU product is approved only for dogs. According to the FDA, the new formulation contains benzyl benzoate and propylene glycol, inactive ingredients that may be toxic to cats.¹
• It is more concentrated. The new formulation is 160 mg/mL, compared with 80 mg/mL for the original Convenia formulation.¹

Supply and administration

The RTU product is supplied as a 10-mL multiuse vial containing 1,600 mg of cefovecin as a ready-to-use suspension. The product is available by prescription from a licensed veterinarian.¹

According to the FDA announcement, veterinarians should shake the product for 60 seconds before each use. The product should be administered with a 20-gauge needle.¹

The FDA granted the approval to Zoetis Inc, based in Kalamazoo, Michigan.¹

References

1. FDA approves ready-to-use cefovecin injectable for treatment of certain skin infections in dogs. News release. US Food and Drug Administration. October 20, 2026. Accessed October 20, 2026. https://www.fda.gov/animal-veterinary/cvm-updates/fda-approves-ready-use-cefovecin-injectable-treatment-certain-skin-infections-dogs