|Articles|May 12, 2010

Case 2

ALP activity can increase for a variety of reasons in dogs. It is highly sensitive but not very specific, so it can be very confusing, not to mention frustrating, when it's elevated in a dog that appears otherwise healthy.Here are some of the common causes of ALP elevation to consider.1

• Age (immature dogs)

• Drugs-glucocorticoids (endogenous and exogenous), anticonvulsants

• Breed-related elevations-Scottish terriers

• Endocrine disease-hyperadrenocorticism, diabetes mellitus, hypothyroidism

• Hepatic nodular hyperplasia

• Hepatic neoplasia-primary or metastatic

• GI disease

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