
Preclinical testing at The Ohio State University found Telomir-Zn inhibited growth of canine and human osteosarcoma cell lines, prompting the company to explore a possible in-vivo study in dogs with naturally occurring tumors.
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This conclusion could not be established without knowledge of the patient's hydration status, status of serum urea and creatinine concentrations and perhaps a water deprivation and vasopressin response test. At least some nephrons must be functioning to concentrate glomerular filtrate (specific gravity = 1.008-1.012) to a specific gravity of 1.020. However, urine specific gravity values of randomly obtained urine samples are usually ≥ 1.040. Further evaluation of this patient is warranted.





