Why it is difficult to make a definitive diagnosis.
Untitled Document
“With only routine H&E stains it can be difficult to make an accurate diagnosis of a histiocytic disease. Diseases that have been confused with the histiocytic disorders based on morphologic appearance include lymphomatoid pulmonary granulomatosis, large cell anaplastic carcinoma of the lung and granulomatous inflammatory conditions.”
-Kim L. Cronin, DVM, DACVIM
From Deciphering the histiocytic code