
- dvm360 November-December 2025
- Volume 56
- Issue 6
Keep healing. Even if the E-collar comes off
KeraVet Gel is the new standard of wound and incision care.
This content is sponsored by KeraVet.
THERE’S NOTHING QUITE like a good recheck. The wound looks great, the patient’s tail is wagging, the client is beaming, and you’re the hero of the day. Then there’s the other kind of recheck, the one with the uncomfortable conversation about why the wound or incision is worse, healing is delayed, and why there may be another bill. That’s the wound care story KeraVet Gel is rewriting.
KeraVet Gel is the first and only keratin based hydrogel for pets that helps wounds and incisions heal faster, thanks to the power of keratin and a strong and safe lick deterrent. The result: less Elizabethan-collar (E-collar) drama, fewer rechecks, and a smoother healing journey all around.
Where science meets common sense
Wound management in veterinary medicine has always been a juggling act: long healing times, licking, chewing, and the endless E-collar struggles that test even the most amazing clients. KeraVet Gel changes that with a novel approach by pairing keratin science with clinical practicality.
How KeraVet Gel works
Macrophages: From angry to helpful
Effective wound and incision healing requires a controlled transition from the inflammatory phase to tissue repair. Studies show that the keratin in KeraVet Gel promotes the polarization of macrophages from the proinfl ammatory M1 state to the antiinfl ammatory M2 state. M2 macrophages play a critical role in tissue repair and wound resolution, creating a microenvironment that supports regeneration rather than chronic infl ammation.
Regulation of cytokines: Turning down the noise
Keratin within the hydrogel directly infl uences cytokine activity, as follows:
- Proinflammatory cytokine suppression: IL-1, IL-6, and TNF-α are downregulated, reducing unnecessary tissue damage during the early stages of healing.
- Anti-inflammatory cytokine promotion: IL-10 is upregulated, further dampening excessive inflammatory responses and supporting balanced immune activity.
Matrix remodeling: Building the scaffolding
Keratin acts like a natural extracellular matrix, providing a biological scaffold that promotes cell adhesion, proliferation, and migration. That means quicker reepithelialization, stronger tissue integrity, and faster wound closure.
Patients actually leave wounds alone
We know that even the best science can’t heal a wound or incision if the patient won’t stop licking it. That’s why KeraVet Gel includes bitterant, clinically proven to reduce licking by up to 87%. Less licking means fewer pathogens, less tissue damage, and if the cone comes o , healing continues.
One product, many clinical advantages
- Keratin-powered healing: Clinically proven to support faster recovery by reducing edema and chronic inflammation and promoting healthy tissue growth.
- Simplified protocol: Replaces the need for multiple adjunct therapies with 1 reliable, easy-to-use gel.
- Nontoxic and nonirritating: Safety assessments confirm that KeraVet Gel is nontoxic, nonirritating, and nonsensitizing.
- Cone or no cone, healing continues: Patients treated with KeraVet Gel require less time in E-collars, and often none at all.
By minimizing self-licking and simplifying wound care, KeraVet Gel increases client follow-through.
Clinical use cases: The gel works just about everywhere
From general practice to urgent, emergency, and specialty care, KeraVet Gel is tough enough for your hardest cases and simple enough for your routine ones. It works across a wide range of cases: bite wounds, surgical incisions, lick granulomas, clipper burns, hot spots, degloving injuries, and even chronic nonhealing wounds.
Following surgical removal of a mass adherent to the biceps femoris muscle, Charlie’s incision dehisced at the skin level due to high limb motion. The site became infected, and after another wound ointment failed, Kimberly Focht, DVM, prescribed KeraVet Gel. “Within 12 hours, the area looked improved, with less wetness and redness,” she said.
The end of “uh-oh” rechecks
KeraVet Gel redefines what’s possible in veterinary wound and incision care by bringing advanced immunological science to everyday clinical practice. By reducing excessive inflammation, supporting tissue regeneration, and easing the E-collar struggle, KeraVet Gel advances the standard of care for dogs and cats.
KeraVet Gel is not just another topical; it is smart, simple wound care that works. To explore the science behind KeraVet Gel, including clinical study results and case studies, visit. https://keravetbio.com/science?utm_source=digital&utm_medium=ad_dvm360vma&utm_campaign=keravetgel_relaunch_2025&utm_id=epiq
Articles in this issue
6 days ago
Fast fixes for itchy dogs15 days ago
The challenges of equine foot lamenessNewsletter
From exam room tips to practice management insights, get trusted veterinary news delivered straight to your inbox—subscribe to dvm360.





