• Hero Banner
  • ACVCACVC
  • DVM 360
  • Fetch DVM 360Fetch DVM 360
DVM 360
dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care
dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care
By Role
AssociatesOwnersPractice ManagerStudentsTechnicians
Subscriptions
dvm360 Newsletterdvm360 Magazine
News
All News
Association
Breaking News
Education
Equine
FDA
Law & Ethics
Market Trends
Medical
Products
Recalls
Regulatory
Digital Media
dvm360 LIVE!™
Expert Interviews
The Vet Blast Podcast
Medical World News
Pet Connections
The Dilemma Live
Vet Perspectives™
Weekly Newscast
dvm360 Insights™
Publications
All Publications
dvm360
Firstline
Supplements
Top Recommended Veterinary Products
Vetted
Clinical
All Clinical
Anesthesia
Animal Welfare
Behavior
Cardiology
CBD in Pets
Dentistry
Dermatology
Diabetes
Emergency & Critical Care
Endocrinology
Equine Medicine
Exotic Animal Medicine
Feline Medicine
Gastroenterology
Imaging
Infectious Diseases
Integrative Medicine
Nutrition
Oncology
Ophthalmology
Orthopedics
Pain Management
Parasitology
Pharmacy
Surgery
Toxicology
Urology & Nephrology
Virtual Care
Business
All Business
Business & Personal Finance
Buying or Selling a Practice
Hospital Design
Leadership & Personal Growth
Personnel Management
Practice Finances
Practice Operations
Technology
Wellbeing & Lifestyle
Continuing Education
Conferences
Live Conferences
Conference News
Conference Proceedings
Resources
CBD in Pets
Contests
Veterinary Heroes
Partners
Spotlight Series
Team Meeting in a Box
Toolkit
Top Recommended Veterinary Products
Vet to Vet
  • Contact Us
  • Fetch DVM360 Conference
  • Terms and Conditions
  • Privacy
  • Do Not Sell My Information
  • About Us

© 2023 MJH Life Sciences and dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care. All rights reserved.

Advertisement
By Role
  • Associates
  • Owners
  • Practice Manager
  • Students
  • Technicians
Subscriptions
  • dvm360 Newsletter
  • dvm360 Magazine
  • Contact Us
  • Fetch DVM360 Conference
  • Terms and Conditions
  • Privacy
  • Do Not Sell My Information
  • About Us
  • MJHLS Brand Logo

© 2023 MJH Life Sciences™ and dvm360 | Veterinary News, Veterinarian Insights, Medicine, Pet Care. All rights reserved.

Journal Scan: Darbepoetin for treatment of anemia in cats with CKD

July 9, 2012
Avi Blake, DVM

Can this drug help eliminate this complication of chronic kidney disease in cats?

Erythropoiesis is largely controlled by the kidney's production of erythropoietin in response to anemia. In cats with chronic kidney disease, 30% to 65% have an associated anemia. The use of erythropoiesis-stimulating agents has been associated with a number of complications in cats, including a pure red cell aplasia, rendering patients transfusion-dependent. Darbepoetin is an effective erythropoiesis-stimulating agent in people, but there is little data on its use in companion animals.

What they did

A recent study evaluated 25 cats seen at the Animal Medical Center in New York between 2005 and 2009 that received two or more doses of darbepoetin, had chronic kidney disease, and had follow-up information available for at least 56 days.

What they found

Advertisement

Of the 25 cats, 14 responded to darbepoetin-all but one receiving a dose of 1 µg/kg/week or higher. The adverse events possibly attributable to darbepoetin included vomiting, hypertension, seizures, and fever.

Take-home message

Darbepoetin was effective for treating anemia associated with chronic kidney disease in cats. Additionally, the results suggest that pure red cell aplasia is less common with the use of darbepoetin than with the use of other erythropoiesis-stimulating agents.

Chalhoub S, Langston CE, Farrelly J. The use of darbepoetin to stimulate erythropoiesis in anemia of chronic kidney disease in cats: 25 cases. J Vet Intern Med 2012;26(2):363-369.

Link to abstract: http://onlinelibrary.wiley.com/doi/10.1111/j.1939-1676.2011.00864.x/abstract

This “Journal Scan” was provided by Avi Blake, DVM, a freelance technical editor and writer in Eudora, Kan.

Related Content:

Clinical
Free microchipping event to take place in Chicago
Free microchipping event to take place in Chicago
Morris Animal Foundation funds study on environmental toxins and lymphoma
Morris Animal Foundation funds study on environmental toxins and lymphoma
Study evaluating potential treatment for degenerative myelopathy receives funding
Study evaluating potential treatment for degenerative myelopathy receives funding

Advertisement

Latest News

Novel vaccine on the market for viruses in pigs

3 Must-reads for World Oceans Day

Research reveals efficacy of non-surgical contraceptive alternative for cats

Potential blood transfusion may offer lion chance of survival

View More Latest News
Advertisement